Mark Waghorn reports,
Surprisingly, results pointed to an unexpected role of proteins and processes that control a form of cell death called ferroptosis. This process happens when iron builds up and weakens a tumor’s metabolism and cell membranes.
“We now know that the CAIX enzyme blocks cancer cells from dying as a result of ferroptosis,” Dr. Dedhar adds. “Combining inhibitors of CAIX, including SLC-0111, with compounds known to bring about ferroptosis results in catastrophic cell death and debilitates tumor growth.”
A large international effort is currently underway to identify drugs that induce ferroptosis. The study is a major step forward in this quest.
Read more here: https://www.studyfinds.org/cancers-achilles-heel/
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