Painful truth of reality versus blissful ignorance of illusion

Since I am not much of a movie-goer, or movie-watcher, I had not heard of the concepts of red pill and blue pill. Wikipedia says,

The red pill and its opposite, the blue pill, are pop culture symbols representing the choice between embracing the sometimes painful truth of reality (red) and the blissful ignorance of illusion (blue).

The terms, popularized in science fiction culture, derive from the 1999 film The Matrix. In the movie, the main character Neo is offered the choice between a red pill and a blue pill. The blue pill would allow him to remain in the fabricated reality of the Matrix. The red pill would lead to his escape from the Matrix and into the "real world".