Fighting antibiotic-resistant bacteria with nanoparticles

Peter Dockrill writes at Science Alert,

Bacterial resistance to antibiotics is a growing problem around the world, responsible for some 2 million infections in the US each year that lead to approximately 23,000 deaths.

But a new nanoparticle treatment developed by researchers at the University of Colorado Boulder could provide an effective means of fighting antibiotic-resistant bacteria including Salmonella, E. Coli, and Staphylococcus, based on results in a laboratory environment. In testing with a lab-grown culture, the nanoparticles killed 92 percent of drug-resistant bacterial cells while leaving the other cells intact.

The treatment consists of light-activated therapeutic nanoparticles called "'quantum dots". These extremely small particles, which resemble the semiconductors used in electronics, are about 20,000 times smaller than a human hair, and when excited by light they prove deadly to drug-resistant bacterial cells.

"By shrinking these semiconductors down to the nanoscale, we're able to create highly specific interactions within the cellular environment that only target the infection," said Prashant Nagpal, senior author of the study published in Nature Materials.

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